Spicy Buffalo Seasoning Blend – Spice up Everything!

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If you like Buffalo wings, then you’re going to love this homemade Buffalo seasoning blend recipe. This spicy blend will add mega flavor to your favorite Buffalo-inspired chicken recipes.

buffalo seasoning blend ingredients on a wooden board

I might be addicted to Frank’s Red Hot Buffalo Sauce. I love the spicy, vinegary tang of this world-famous wing sauce. Shredded chicken drowning in hot sauce straight out of the slow cooker is one of my favorite comfort foods. Of course, it’s always amazing on some classic chicken wings.

At least once a week, I bake a batch of chicken breasts just so I have them in the fridge ready to go for a quick and easy weeknight meal. One of my favorite flavor combos when I’m cooking chicken is an easy Buffalo chicken recipe.

However, I also use this seasoning blend to make Buffalo Chicken Eggrolls and my Buffalo Chicken Dip. Both of these family loved recipes are perfect for Super Bowl snacking. And don’t forget about my Gourmet Buffalo Shrimp Jalapeño Poppers.

This spicy chicken is also featured in my Buffalo Chicken Meal Prep Bowl which is a low carb, keto meal prep bowl with all the flavor you crave in a big ol’ plate of hot wings. It’s healthy and so delicious.

What You’ll Love About This Recipe

  • Easy. Having this spice mix on hand makes meal prep super easy. Mix up a bunch of these sweet and spicy mixes and keep them in your cupboard!
  • Quick. When you’re wanting all-day flavor but only want to spend like 15 minutes or 30 minutes at the most, this spice combo is magical. Transform boring chicken or veggies with just a quick sprinkle. Genius.

Recipe Notes

Making homemade spice blends only requires one thing: fresh, high quality spices. I usually buy spices from Mountain Rose Herbs (affiliate link) and Penzey’s (affiliate link).

I make a lot of different spice blends that I keep on hand all the time. It’s seriously my secret weapon for ultra-fast meal prep. Seasoning blends are easy chicken recipes’ best friend.

Check out my post on Seasoning Blends and setting up your spice cabinet.

Ingredients for Buffalo Seasoning Blend

ingredients for buffalo seasoning mix
  • Garlic granules — I use dried garlic granules instead of garlic powder because I find that it keeps better in a blend. The fine powder tends to cake up.
  • Onion granules — Same for the onion granules! Of course, in a pinch, onion powder will work.
  • Paprika — Use sweet paprika in this recipe, or experiment with smoked paprika!
  • Cayenne pepper — Adjust the amount of cayenne pepper to suit your palate. I like mine spicy, so I always add more.
  • Salt and pepper — I use Kosher salt or Himalayan salt in almost everything I cook.

Step-by-Step Instructions

There’s only one step here. Measure and mix all of the ingredients.

Yep, that’s it! Store in an airtight container.

How to use Buffalo seasoning:

  • Use as a dry rub on grilled chicken breasts or baked chicken thighs.
  • Sprinkle on shrimp and pan sear in olive oil on medium high heat, or make these bacon-wrapped shrimp.
  • Add to chicken, cook in an Instant Pot, then shred.
  • Toss chicken wings and drumettes in Buffalo seasoning. Air fry and then add Buffalo wing sauce. Serve with blue cheese dressing and carrots and celery sticks.
buffalo seasoning mix in a jar

FAQs and Expert Tips

What is Buffalo seasoning made of?

Buffalo seasoning is made of garlic, onion, paprika, and cayenne pepper.

What does Buffalo seasoning taste like?

Buffalo seasoning has an unmistakable taste. The combination of garlic, paprika, and cayenne pepper adds a spicy, savory, smoky kick to chicken. When paired with Buffalo sauce, that spicy, vinegary flavor is definitely addictive.

How to use Buffalo Seasoning Blend

buffalo wings with blue cheese dip

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Other Seasoning Blend Recipes That You’ll Love

buffalo seasoning in an airtight container
buffalo seasoning mix in a jar

Buffalo Seasoning Blend

This Buffalo seasoning blend adds flavor to chicken and shrimp. Add Buffalo flavor fast to wings and easy baked chicken breast.
Prep Time 5 minutes
Total Time 5 minutes
Course Spice Mix
Cuisine American
Servings 12
Calories 9 kcal




  • Measure the spices, mix, and store in an airtight container.


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Calories: 9kcalCarbohydrates: 2gProtein: 1gFat: 1gSaturated Fat: 1gSodium: 583mgFiber: 1gSugar: 1gCalcium: 5mgIron: 1mg
Keyword buffalo chicken, Spice Mix
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  1. 5 stars
    This is a terrific spice blend! I used it as a rub on chicken tenders and air fried them, then tossed in some buffalo sauce and it was sooooo good. I have to follow a very low sodium diet so I used Mortonโ€™s no sodium salt substitute instead of salt and dropped that to 1.5 tsp and make it zero sodium. Fantastic!

  2. I could kiss you! I ran out of my powdered Frankโ€™s seasoning mid recipe, due to pure irresponsibility & poor life choices that I repeat daily. I couldnโ€™t tell the difference in the half of chicken done with your recipe and the Franks. They say heroes wear all sized capes, and yours my dear, is firey red with the franks red hot label smack dab in the middle. Xo -Liberty

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